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Y4 Oxygen-First Method™

A physiology-driven framework for preventive and executive health, Y4 Oxygen-First is a medical framework focused on how efficiently the body delivers, stabilizes, and utilizes oxygen before disease develops.

The Problem

Modern medicine excels at diagnosing disease once it is established. What it often misses is the early loss of physiologic reserve, the subtle strain that accumulates long before abnormal tests appear.

Many individuals with normal labs and imaging experience:

  • Fatigue
  • Poor recovery
  • Breathlessness under stress
  • Declining performance

These signals are often dismissed because routine testing appears “normal.”

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The Reframe

Oxygen is not just a saturation number.

  • Demand — how much work is required to maintain function
  • Stability — how oxygen delivery behaves during sleep and stress
  • Reserve — the margin available when demand increases

Loss of reserve often appears first, before disease is detectable.

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The Y4 Framework

Oxygen & Respiration

Efficiency of ventilation, airway mechanics, and gas exchange not just resting values.

Sleep & Recovery

Overnight oxygen stability, sleep fragmentation, and neurologic recovery capacity.

Metabolic Resilience

How effectively oxygen is converted into usable energy at the cellular level.

Cognitive & Stress Load

The physiologic oxygen demand created by chronic stress and high cognitive output.

Who This Is For

Clinic example

Professionals and executives with sustained cognitive or physical demands

Clinic example

Individuals with fatigue or reduced resilience despite “normal” testing

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Those seeking upstream prevention rather than late-stage intervention

What This Is Not

  • Not biohacking
  • Not breathwork
  • Not a performance shortcut
  • Not a replacement for specialty medical care

Y4 Oxygen-First is a framework, not a protocol - grounded in physiology and personalized.

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About Y4 Oxygen

Kashif Yaqub, MD

Pulmonary & Internal Medicine

Executive and Preventive Health

Y4 Oxygen-First reflects a clinical focus on upstream physiology, integrative care, and long-term resilience.

For membership inquiries:
Phone: (949) 678-8885
Email: info@keymdnewport.com

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